Sandstone-type uranium deposits are the main type of uranium resources in China. Geophysical exploration methods are widely used to explore energy and mineral resources such as oil, gas, and coal in sedimentary basins, and they should also play an important role in the exploration of sandstone-type uranium deposits. Based on actual exploration conditions, this paper explores the current application status, existing problems, and development trends of geophysical exploration methods from the aspects of the metallogenic theory and ore-controlling factors of sandstone-type uranium deposits. In practical application, geophysical logging plays an important role in the direct positioning of uranium deposits and the quantitative calculation of uranium content per square meter, while the surface geophysical methods enjoy advantages in ascertaining uranium metallogenic environments such as sedimentary suites, faults, the lithology of rock masses, and basement relief. To ensure the application effects of geophysical exploration methods, it is necessary to closely combine the existing geological information in the whole process of method selection, survey line arrangement, and data processing and interpretation. Meanwhile, it is also necessary to select comprehensive geophysical exploration methods as required by actual conditions. It should be emphasized that the gravity and magnetic data can provide bases for the selection of optimal exploration areas inside basins and the arrangement of geological and geophysical exploration in the late stage. Therefore, enough attention should be paid to them in the prospecting and preliminary exploration work of uranium deposits.