Abstract: The deployment of video monitoring points for epidemic prevention in border areas is an important measure to deal with emergencies and has great significance for regional public health security. The deployment of video monitoring points mainly focused on cities in the past. Few studies concerned the deployment of video monitoring points based on the characteristics of border areas and emergency response needs. This study constructed a framework for the deployment of video monitoring points for epidemic prevention in the border area of Xishuangbanna Dai Autonomous Prefecture. The suitability and limiting factors of monitoring points were determined for the multi-round selection of monitoring points. More monitoring points were deployed properly in areas with low monitoring efficiency. Finally, the appropriate deployment sites for epidemic prevention monitoring points in Xishuangbanna were determined. The results are as follows. With the video monitoring points for epidemic prevention determined in this study, 93.3% of the area within 5 km of the Xishuangbanna border can be observed. Thus, information on people flow at the border can be comprehensively obtained. Compared with the conventional site selection methods using single-dimensional suitability, mathematical modeling, and algorithms, the proposed deployment method of video monitoring points for border epidemic prevention is more suitable for the actual situation of border areas and can give full play to the overall coordination level of the deployment of monitoring points. Besides, this proposed method avoids the complex application of conventional methods. Therefore, the site selection method of video monitoring points for epidemic prevention proposed in this study provides theoretical reference and technical support for current COVID-19 prevention in border areas, so as to ensure regional public health security and national sustainable development.