Remote Sensing (RS), Global Positioning System (GPS), and Geographical Information System (GIS) are being rapidly developped, in the meantime, they are forging ahead toward the Integration and resulting in the so-called “3S-Integration”. The 3S-Integration gives a new and great potential technical support to the investigation and research of seismic hazards. In this paper, the application of 3S-Techniques to investigate and study seismic hazards are briefly described, and , in the point view of Integration emphatically, the use model and realizations of 3S-Integration in the futural investigation and research of seismic hazards aer discussed.