In many kinds of geochemical exploration methods such as acidolysis hydrocarbon, dissolved hydrocarbon and thermally released hydrocarbon, the geochemical pretreatment of the sample is very important. Nevertheless, China's sample retreatment technique remains at the stage of manual operation, which does not match the widely used high-precision analytical instruments. On the basis of researches on the intelligent-control geochemical sample pretreatment system, this paper deals with in detail the working mechanism, control structures, implementation methods, performance indexes and quality inspection results of this system, and describes the application achievements in gas hydrate exploration with acidolysis hydrocarbon methods in ODP204 and dissolved hydrocarbon methods in Dongsha area, the South China Sea. Practices have proved that the intelligent-control system is capable of completing the geochemical sample pretreatment work under the automatic condition, and has properties of fastness, precision, safety and portableness. It has promising application prospect in China's marine gas hydrates exploration and terrestrial petroleum geochemical exploration, and also has great significance for improving China's geochemical sample pretreatment equipment techniques.