This study aims to ascertain the heavy metal pollution of groundwater in a typical chemical industry park in northwestern Shandong. According to the investigation and evaluation requirements for groundwater environments in chemical industry parks, this study collected 10 groundwater samples to analyze the concentrations and spatial distributions of eight heavy metals, namely Fe, Cu, Zn, Al, Cd and Pb. Furthermore, it conducted the health risk assessment of groundwater for different populations. The results indicate that: (1) except Mn and Al, all heavy metals in the groundwater of the chemical industry park showed concentrations lower than the class III water quality standard stated in the Standard for Groundwater Quality (GB/T 14848—2017), with a comprehensive pollution index ranging from 0.37 to 0.78. The monitoring points for heavy metal elements are all pollution-free; (2) the overall spatial distributions of heavy metals are roughly consistent with the distribution areas of key enterprises in the chemical industry park. This consistency indicates that external factors such as the production activities of enterprises affect the spatial distributions of heavy metals in groundwater; (3) the health risks are lower for children than for adults and lower via skin contact than via drinking. The non-carcinogenic risks under different exposure routes are acceptable for different populations. Carcinogens As and Cd have slight carcinogenic risks for adults. Local authorities should strengthen the supervision of the production activities of enterprises and thoroughly inspect enterprises with suspected pollution. Only in this way can we effectively control and then gradually reduce the risks to human health caused by groundwater pollution.