Based on remote sensing monitoring and investigation combined with data of Quaternary geology, the authors studied and analyzed the change process of the Yellow River course in Yinchuan plain sector. It is found that the Yellow River in Yinchuan plain sector was formed in Early Pleistocene and the river course frequently moved eastward after that. In Middle and Late Pleistocene, the river course grew remarkably. In Holocene, the sediments of the Yellow River formed the main body of the Yinchuan plain, with several old river courses left on it. In recent years, the river course has become increasingly narrower and remained shifting eastward.