In this paper, Wuhan City was selected for case study. Land use information obtained from satellite remote sensing TM image in 2000 and 2005 was used as the main data source, and the GIS technology was employed as the data integration analysis platform. An ecological risk index was constructed based on the varieties of land use, and the systematic sampling method was utilized to make it a spatial variable. After the performance of sampling, the semivariagram analysis and block kriging were conducted to compile the map of ecological risk distribution. The results indicate that the spatial distribution of ecological risk became more uneven in the working area. The level of the ecological risk study area was divided into three levels: the majority of the vegetation and the waters belonged to the low ecological risk area, whereas the urban built-up area and its marginal areas belonged to moderate ecological risk and relatively high risk areas. Spatial distribution of areas of various levels experienced certain extent of changes in the five years.